In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Targeted genome editing via engineered nucleases is an exciting area of biomedical research and holds potential for clinical applications. Despite rapid advances in the field, in vivo targeted transgene integration is still infeasible because current tools are inefficient(1), especially for non-divi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nature
Autori principali: Suzuki, Keiichiro, Tsunekawa, Yuji, Hernandez-Benitez, Reyna, Wu, Jun, Zhu, Jie, Kim, Euiseok J., Hatanaka, Fumiyuki, Yamamoto, Mako, Araoka, Toshikazu, Li, Zhe, Kurita, Masakazu, Hishida, Tomoaki, Li, Mo, Aizawa, Emi, Guo, Shicheng, Chen, Song, Goebl, April, Soligalla, Rupa Devi, Qu, Jing, Jiang, Tingshuai, Fu, Xin, Jafari, Maryam, Esteban, Concepcion Rodriguez, Berggren, W. Travis, Lajara, Jeronimo, Nuñez-Delicado, Estrella, Guillen, Pedro, Campistol, Josep M., Matsuzaki, Fumio, Liu, Guang-Hui, Magistretti, Pierre, Zhang, Kun, Callaway, Edward M., Zhang, Kang, Belmonte, Juan Carlos Izpisua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331785/
https://ncbi.nlm.nih.gov/pubmed/27851729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20565
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi