Mutations in foregut SOX2(+) cells induce efficient proliferation via CXCR2 pathway

Identification of the precise molecular pathways involved in oncogene-induced transformation may help us gain a better understanding of tumor initiation and promotion. Here, we demonstrate that SOX2(+) foregut epithelial cells are prone to oncogenic transformation upon mutagenic insults, such as Kra...

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Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Hishida, Tomoaki, Vazquez-Ferrer, Eric, Hishida-Nozaki, Yuriko, Sancho-Martinez, Ignacio, Takahashi, Yuta, Hatanaka, Fumiyuki, Wu, Jun, Ocampo, Alejandro, Reddy, Pradeep, Wu, Min-Zu, Gerken, Laurie, Shaw, Reuben J., Rodriguez Esteban, Concepcion, Benner, Christopher, Nakagawa, Hiroshi, Guillen Garcia, Pedro, Nuñez Delicado, Estrella, Castells, Antoni, Campistol, Josep M., Liu, Guang-Hui, Izpisua Belmonte, Juan Carlos
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588654/
https://ncbi.nlm.nih.gov/pubmed/31041783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-019-0630-3
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