Massively multiplex single-cell Hi-C

We present single-cell combinatorial indexed Hi-C (sciHi-C), which applies the concept of combinatorial cellular indexing to chromosome conformation capture. In this proof-of-concept, we generate and sequence six sciHi-C libraries comprising a total of 10,696 single cells. We use sciHi-C data to sep...

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Bibliografske podrobnosti
izdano v:Nat Methods
Main Authors: Ramani, Vijay, Deng, Xinxian, Qiu, Ruolan, Gunderson, Kevin L, Steemers, Frank J, Disteche, Christine M, Noble, William S, Duan, Zhijun, Shendure, Jay
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330809/
https://ncbi.nlm.nih.gov/pubmed/28135255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4155
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