Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder initiated by antibodies against complexes between human platelet factor 4 (hPF4) and heparin. A better understanding of the events that initiate the prothrombotic state may improve approaches to antithrombotic management. Here, we vi...

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Publicado en:J Clin Invest
Autores principales: Hayes, Vincent, Johnston, Ian, Arepally, Gowthami M., McKenzie, Steven E., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330743/
https://ncbi.nlm.nih.gov/pubmed/28218620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90958
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