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AIF deficiency compromises oxidative phosphorylation
Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show that human or mouse cells lacking AIF as a result of homologous recombination or small interfering RNA exhibi...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Nature Publishing Group
2004
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC533047/ https://ncbi.nlm.nih.gov/pubmed/15526035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600461 |
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