AIF deficiency compromises oxidative phosphorylation

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show that human or mouse cells lacking AIF as a result of homologous recombination or small interfering RNA exhibi...

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Main Authors: Vahsen, Nicola, Candé, Céline, Brière, Jean-Jacques, Bénit, Paule, Joza, Nicholas, Larochette, Nathanael, Mastroberardino, Pier Giorgio, Pequignot, Marie O, Casares, Noelia, Lazar, Vladimir, Feraud, Olivier, Debili, Najet, Wissing, Silke, Engelhardt, Silvia, Madeo, Frank, Piacentini, Mauro, Penninger, Josef M, Schägger, Hermann, Rustin, Pierre, Kroemer, Guido
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC533047/
https://ncbi.nlm.nih.gov/pubmed/15526035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600461
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