AIF deficiency compromises oxidative phosphorylation

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show that human or mouse cells lacking AIF as a result of homologous recombination or small interfering RNA exhibi...

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Detalhes bibliográficos
Main Authors: Vahsen, Nicola, Candé, Céline, Brière, Jean-Jacques, Bénit, Paule, Joza, Nicholas, Larochette, Nathanael, Mastroberardino, Pier Giorgio, Pequignot, Marie O, Casares, Noelia, Lazar, Vladimir, Feraud, Olivier, Debili, Najet, Wissing, Silke, Engelhardt, Silvia, Madeo, Frank, Piacentini, Mauro, Penninger, Josef M, Schägger, Hermann, Rustin, Pierre, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533047/
https://ncbi.nlm.nih.gov/pubmed/15526035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600461
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