AIF deficiency compromises oxidative phosphorylation

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show that human or mouse cells lacking AIF as a result of homologous recombination or small interfering RNA exhibi...

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Autors principals: Vahsen, Nicola, Candé, Céline, Brière, Jean-Jacques, Bénit, Paule, Joza, Nicholas, Larochette, Nathanael, Mastroberardino, Pier Giorgio, Pequignot, Marie O, Casares, Noelia, Lazar, Vladimir, Feraud, Olivier, Debili, Najet, Wissing, Silke, Engelhardt, Silvia, Madeo, Frank, Piacentini, Mauro, Penninger, Josef M, Schägger, Hermann, Rustin, Pierre, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533047/
https://ncbi.nlm.nih.gov/pubmed/15526035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600461
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