Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays

Zika virus (ZIKV) is an emerging human pathogen that is spreading rapidly through the Americas and has been linked to the development of microcephaly and to a dramatically increased number of Guillain-Barré syndrome cases. Currently, no vaccine or therapeutic options for the prevention or treatment...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lu, Gaofei, Bluemling, Gregory R., Collop, Paul, Hager, Michael, Kuiper, Damien, Gurale, Bharat P., Painter, George R., De La Rosa, Abel, Kolykhalov, Alexander A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328514/
https://ncbi.nlm.nih.gov/pubmed/27993851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01967-16
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