Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays

Zika virus (ZIKV) is an emerging human pathogen that is spreading rapidly through the Americas and has been linked to the development of microcephaly and to a dramatically increased number of Guillain-Barré syndrome cases. Currently, no vaccine or therapeutic options for the prevention or treatment...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lu, Gaofei, Bluemling, Gregory R., Collop, Paul, Hager, Michael, Kuiper, Damien, Gurale, Bharat P., Painter, George R., De La Rosa, Abel, Kolykhalov, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328514/
https://ncbi.nlm.nih.gov/pubmed/27993851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01967-16
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