Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays

Zika virus (ZIKV) is an emerging human pathogen that is spreading rapidly through the Americas and has been linked to the development of microcephaly and to a dramatically increased number of Guillain-Barré syndrome cases. Currently, no vaccine or therapeutic options for the prevention or treatment...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Lu, Gaofei, Bluemling, Gregory R., Collop, Paul, Hager, Michael, Kuiper, Damien, Gurale, Bharat P., Painter, George R., De La Rosa, Abel, Kolykhalov, Alexander A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328514/
https://ncbi.nlm.nih.gov/pubmed/27993851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01967-16
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