Induction of alternative proinflammatory cytokines accounts for sustained psoriasiform skin inflammation in IL-17C+IL-6KO mice

IL-6 inhibition has been unsuccessful in treating psoriasis, despite high levels of tissue and serum IL-6 in patients. Additionally, de novo psoriasis onset has been reported following IL-6 blockade in rheumatoid arthritis patients. To explore mechanisms underlying these clinical observations, we ba...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Invest Dermatol
Egile Nagusiak: Fritz, Yi, Klenotic, Philip A., Swindell, William R., Yin, ZhiQiang, Groft, Sarah G., Zhang, Li, Baliwag, Jaymie, Camhi, Maya I., Diaconu, Doina, Young, Andrew B., Foster, Alexander M., Johnston, Andrew, Gudjonsson, Johann E., McCormick, Thomas S., Ward, Nicole L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326585/
https://ncbi.nlm.nih.gov/pubmed/27984037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.10.021
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