Induction of alternative proinflammatory cytokines accounts for sustained psoriasiform skin inflammation in IL-17C+IL-6KO mice

IL-6 inhibition has been unsuccessful in treating psoriasis, despite high levels of tissue and serum IL-6 in patients. Additionally, de novo psoriasis onset has been reported following IL-6 blockade in rheumatoid arthritis patients. To explore mechanisms underlying these clinical observations, we ba...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Invest Dermatol
Autori principali: Fritz, Yi, Klenotic, Philip A., Swindell, William R., Yin, ZhiQiang, Groft, Sarah G., Zhang, Li, Baliwag, Jaymie, Camhi, Maya I., Diaconu, Doina, Young, Andrew B., Foster, Alexander M., Johnston, Andrew, Gudjonsson, Johann E., McCormick, Thomas S., Ward, Nicole L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326585/
https://ncbi.nlm.nih.gov/pubmed/27984037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.10.021
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi