IL-36 promotes myeloid cell infiltration, activation and inflammatory activity in skin

The IL-1 family members IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) and the receptor antagonist IL-36Ra (IL-1F5) constitute a novel signaling system that is poorly understood. We now show that these cytokines have profound effects on the skin immune system. Treatment of human keratinocytes...

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Detalhes bibliográficos
Main Authors: Foster, Alexander M., Baliwag, Jaymie, Chen, Cynthia S., Guzman, Andrew M., Stoll, Stefan W., Gudjonsson, Johann E., Ward, Nicole L., Johnston, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048788/
https://ncbi.nlm.nih.gov/pubmed/24829417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301481
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