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EGFR and IL-1 signaling synergistically promote keratinocyte antimicrobial defenses in a differentiation-dependent manner

Ligands of the EGF family regulate autocrine keratinocyte proliferation and IL-1 family cytokines orchestrate epithelial defense responses. While members of both families are overexpressed in wound healing and psoriasis, their roles in regulating the innate immune functions of keratinocytes remain i...

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Autors principals: Johnston, Andrew, Gudjonsson, Johann E., Aphale, Abhishek, Guzman, Andrew M., Stoll, Stefan W., Elder, James T
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094455/
https://ncbi.nlm.nih.gov/pubmed/20962853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.313
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