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METALLOPROTEINASE-MEDIATED, CONTEXT-DEPENDENT FUNCTION OF AMPHIREGULIN AND HB-EGF IN HUMAN KERATINOCYTES AND SKIN

Human keratinocytes (KCs) express multiple EGF receptor (EGFR) ligands; however, their functions in specific cellular contexts remain largely undefined. To address this issue, first we measured mRNA and protein levels for multiple EGFR ligands in KCs and skin. Amphiregulin (AREG) was by far the most...

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Detalhes bibliográficos
Main Authors: Stoll, Stefan W., Johnson, Jessica L., Bhasin, Ajay, Johnston, Andrew, Gudjonsson, Johann E., Rittié, Laure, Elder, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795126/
https://ncbi.nlm.nih.gov/pubmed/19609315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2009.211
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