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AMPHIREGULIN CARBOXY-TERMINAL DOMAIN IS REQUIRED FOR AUTOCRINE KERATINOCYTE GROWTH

The EGF receptor ligand amphiregulin (AREG) has been implicated as an important autocrine growth factor in several epithelial malignancies and in psoriasis, a hyperproliferative skin disorder. To characterize the mechanisms by which AREG regulates autocrine epithelial cell growth, we transduced huma...

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Detalhes bibliográficos
Main Authors: Stoll, Stefan W., Johnson, Jessica L., Li, Yong, Rittié, Laure, Elder, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072808/
https://ncbi.nlm.nih.gov/pubmed/20428186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.98
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