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AMPHIREGULIN CARBOXY-TERMINAL DOMAIN IS REQUIRED FOR AUTOCRINE KERATINOCYTE GROWTH
The EGF receptor ligand amphiregulin (AREG) has been implicated as an important autocrine growth factor in several epithelial malignancies and in psoriasis, a hyperproliferative skin disorder. To characterize the mechanisms by which AREG regulates autocrine epithelial cell growth, we transduced huma...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072808/ https://ncbi.nlm.nih.gov/pubmed/20428186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.98 |
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