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Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation
The EGF receptor (EGFR) and its ligands are essential regulators of epithelial biology, which are often amplified in cancer cells. We have previously shown that shRNA-mediated silencing of one of these ligands, amphiregulin (AREG), results in keratinocyte growth arrest that cannot be rescued by solu...
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| Publicado no: | J Invest Dermatol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788462/ https://ncbi.nlm.nih.gov/pubmed/26802239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2015.10.061 |
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