Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation

The EGF receptor (EGFR) and its ligands are essential regulators of epithelial biology, which are often amplified in cancer cells. We have previously shown that shRNA-mediated silencing of one of these ligands, amphiregulin (AREG), results in keratinocyte growth arrest that cannot be rescued by solu...

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Detaylı Bibliyografya
Yayımlandı:J Invest Dermatol
Asıl Yazarlar: Stoll, Stefan W., Stuart, Philip E., Lambert, Sylviane, Gandarillas, Alberto, Rittié, Laure, Johnston, Andrew, Elder, James T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788462/
https://ncbi.nlm.nih.gov/pubmed/26802239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2015.10.061
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