Autocrine Extracellular Signal-regulated Kinase (ERK) Activation in Normal Human Keratinocytes: Metalloproteinase-mediated Release of Amphiregulin Triggers Signaling from ErbB1 to ERK

ErbB signaling through extracellular signal-regulated kinase (ERK) has been implicated in regulating the expression of ErbB ligands in hyperproliferative skin disorders and wound healing. Here, we characterize the process of autocrine ERK activation in cultured normal human keratinocytes (NHKs) subj...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Kansra, Sanjay, Stoll, Stefan W., Johnson, Jessica L., Elder, James T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Cell Biology 2004
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC515360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-03-0233
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