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Interleukin 6 regulates psoriasiform inflammation–associated thrombosis
Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...
Shranjeno v:
| izdano v: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/ https://ncbi.nlm.nih.gov/pubmed/27942589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384 |
| Oznake: |
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