Interleukin 6 regulates psoriasiform inflammation–associated thrombosis

Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Wang, Yunmei, Golden, Jackelyn B., Fritz, Yi, Zhang, Xiufen, Diaconu, Doina, Camhi, Maya I., Gao, Huiyun, Dawes, Sean M., Xing, Xianying, Ganesh, Santhi K., Gudjonsson, Johann E., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/
https://ncbi.nlm.nih.gov/pubmed/27942589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384
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