Interleukin 6 regulates psoriasiform inflammation–associated thrombosis

Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wang, Yunmei, Golden, Jackelyn B., Fritz, Yi, Zhang, Xiufen, Diaconu, Doina, Camhi, Maya I., Gao, Huiyun, Dawes, Sean M., Xing, Xianying, Ganesh, Santhi K., Gudjonsson, Johann E., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/
https://ncbi.nlm.nih.gov/pubmed/27942589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384
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