Interleukin 6 regulates psoriasiform inflammation–associated thrombosis

Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Wang, Yunmei, Golden, Jackelyn B., Fritz, Yi, Zhang, Xiufen, Diaconu, Doina, Camhi, Maya I., Gao, Huiyun, Dawes, Sean M., Xing, Xianying, Ganesh, Santhi K., Gudjonsson, Johann E., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/
https://ncbi.nlm.nih.gov/pubmed/27942589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384
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