Interleukin 6 regulates psoriasiform inflammation–associated thrombosis

Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Wang, Yunmei, Golden, Jackelyn B., Fritz, Yi, Zhang, Xiufen, Diaconu, Doina, Camhi, Maya I., Gao, Huiyun, Dawes, Sean M., Xing, Xianying, Ganesh, Santhi K., Gudjonsson, Johann E., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/
https://ncbi.nlm.nih.gov/pubmed/27942589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384
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