Interleukin 6 regulates psoriasiform inflammation–associated thrombosis

Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14(–/–) mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Wang, Yunmei, Golden, Jackelyn B., Fritz, Yi, Zhang, Xiufen, Diaconu, Doina, Camhi, Maya I., Gao, Huiyun, Dawes, Sean M., Xing, Xianying, Ganesh, Santhi K., Gudjonsson, Johann E., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135273/
https://ncbi.nlm.nih.gov/pubmed/27942589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89384
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