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H-Ras Isoform Mediates Protection Against Pressure Overload-Induced Cardiac Dysfunction in Part Through Activation of Akt

BACKGROUND: In general, Ras proteins are thought to promote cardiac hypertrophy, an important risk factor for cardiovascular disease and heart failure. However, the contribution of different Ras isoforms has not been investigated. The objective of this study was to define the role of H- and K-Ras in...

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Dades bibliogràfiques
Publicat a:Circ Heart Fail
Autors principals: Matsuda, Takahisa, Jeong, Jae Im, Ikeda, Shohei, Yamamoto, Takanobu, Gao, Shumin, Babu, Gopal J., Zhai, Peiyong, Del Re, Dominic P.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325037/
https://ncbi.nlm.nih.gov/pubmed/28193718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003658
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