Yes-Associated Protein (YAP) Facilitates Pressure Overload–Induced Dysfunction in the Diabetic Heart

Patients with diabetes are more prone to developing heart failure in the presence of high blood pressure than those without diabetes. Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP plays an essential role in mediatin...

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Bibliographische Detailangaben
Veröffentlicht in:JACC Basic Transl Sci
Hauptverfasser: Ikeda, Shohei, Mukai, Risa, Mizushima, Wataru, Zhai, Peiyong, Oka, Shin-ichi, Nakamura, Michinari, Del Re, Dominic P., Sciarretta, Sebastiano, Hsu, Chiao-Po, Shimokawa, Hiroaki, Sadoshima, Junichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
PRECLINICAL RESEARCH
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872826/
https://ncbi.nlm.nih.gov/pubmed/31768477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.006
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