Yes-Associated Protein (YAP) Facilitates Pressure Overload–Induced Dysfunction in the Diabetic Heart

Patients with diabetes are more prone to developing heart failure in the presence of high blood pressure than those without diabetes. Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP plays an essential role in mediatin...

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Détails bibliographiques
Publié dans:JACC Basic Transl Sci
Auteurs principaux: Ikeda, Shohei, Mukai, Risa, Mizushima, Wataru, Zhai, Peiyong, Oka, Shin-ichi, Nakamura, Michinari, Del Re, Dominic P., Sciarretta, Sebastiano, Hsu, Chiao-Po, Shimokawa, Hiroaki, Sadoshima, Junichi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
PRECLINICAL RESEARCH
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872826/
https://ncbi.nlm.nih.gov/pubmed/31768477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.006
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