Yes-Associated Protein (YAP) Facilitates Pressure Overload–Induced Dysfunction in the Diabetic Heart

Patients with diabetes are more prone to developing heart failure in the presence of high blood pressure than those without diabetes. Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP plays an essential role in mediatin...

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Vydáno v:JACC Basic Transl Sci
Hlavní autoři: Ikeda, Shohei, Mukai, Risa, Mizushima, Wataru, Zhai, Peiyong, Oka, Shin-ichi, Nakamura, Michinari, Del Re, Dominic P., Sciarretta, Sebastiano, Hsu, Chiao-Po, Shimokawa, Hiroaki, Sadoshima, Junichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
PRECLINICAL RESEARCH
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872826/
https://ncbi.nlm.nih.gov/pubmed/31768477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.006
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