Yes-Associated Protein (YAP) Facilitates Pressure Overload–Induced Dysfunction in the Diabetic Heart

Patients with diabetes are more prone to developing heart failure in the presence of high blood pressure than those without diabetes. Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP plays an essential role in mediatin...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Ikeda, Shohei, Mukai, Risa, Mizushima, Wataru, Zhai, Peiyong, Oka, Shin-ichi, Nakamura, Michinari, Del Re, Dominic P., Sciarretta, Sebastiano, Hsu, Chiao-Po, Shimokawa, Hiroaki, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872826/
https://ncbi.nlm.nih.gov/pubmed/31768477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.006
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