H-Ras Isoform Mediates Protection Against Pressure Overload-Induced Cardiac Dysfunction in Part Through Activation of Akt

BACKGROUND: In general, Ras proteins are thought to promote cardiac hypertrophy, an important risk factor for cardiovascular disease and heart failure. However, the contribution of different Ras isoforms has not been investigated. The objective of this study was to define the role of H- and K-Ras in...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Matsuda, Takahisa, Jeong, Jae Im, Ikeda, Shohei, Yamamoto, Takanobu, Gao, Shumin, Babu, Gopal J., Zhai, Peiyong, Del Re, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325037/
https://ncbi.nlm.nih.gov/pubmed/28193718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003658
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