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Distinct roles of GSK-3α and GSK-3β phosphorylation in the heart under pressure overload
Glycogen synthase kinase-3 (GSK-3) is a master regulator of growth and death in cardiac myocytes. GSK-3 is inactivated by hypertrophic stimuli through phosphorylation-dependent and -independent mechanisms. Inactivation of GSK-3 removes the negative constraint of GSK-3 on hypertrophy, thereby stimula...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
National Academy of Sciences
2008
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634936/ https://ncbi.nlm.nih.gov/pubmed/19106302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808315106 |
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