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Myocardial Injection with GSK-3β-Overexpressing Bone Marrow-Derived Mesenchymal Stem Cells Attenuates Cardiac Dysfunction after Myocardial Infarction
RATIONALE: Glycogen synthase kinase-3β (GSK-3β) upregulates cardiac genes in bone marrow-derived mesenchymal stem cells (MSCs) in vitro. Ex vivo modification of signaling mechanisms in MSCs may improve the efficiency of cardiac cell based therapy (CRT). OBJECTIVE: To test the effect of GSK-3β upon t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109296/ https://ncbi.nlm.nih.gov/pubmed/21233455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.229658 |
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