Differential Roles of GSK-3β during Myocardial Ischemia and Ischemia/Reperfusion

BACKGROUND: Inhibition of Glycogen synthase kinase-3 (GSK-3) protects the heart during ischemia/reperfusion (I/R). However, the underlying mechanisms of cardioprotection afforded by beta isoform-specific inhibition of GSK-3 remain to be elucidated. METHODS AND RESULTS: We studied the molecular mecha...

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Main Authors: Zhai, Peiyong, Sciarretta, Sebastiano, Galeotti, Jonathan, Volpe, Massimo, Sadoshima, Junichi
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158807/
https://ncbi.nlm.nih.gov/pubmed/21737790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.249532
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