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H-Ras Isoform Mediates Protection Against Pressure Overload-Induced Cardiac Dysfunction in Part Through Activation of Akt
BACKGROUND: In general, Ras proteins are thought to promote cardiac hypertrophy, an important risk factor for cardiovascular disease and heart failure. However, the contribution of different Ras isoforms has not been investigated. The objective of this study was to define the role of H- and K-Ras in...
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Udgivet i: | Circ Heart Fail |
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Main Authors: | , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2017
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325037/ https://ncbi.nlm.nih.gov/pubmed/28193718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003658 |
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