Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

Bile acids are extensively investigated for their potential in the treatment of human disorders. The liver X receptors (LXRs), activated by oxysterols and by a secondary bile acid named hyodeoxycholic acid (HDCA), have been found essential in the regulation of lipid homeostasis in mammals. Unfortuna...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: De Marino, Simona, Carino, Adriana, Masullo, Dario, Finamore, Claudia, Marchianò, Silvia, Cipriani, Sabrina, Di Leva, Francesco Saverio, Catalanotti, Bruno, Novellino, Ettore, Limongelli, Vittorio, Fiorucci, Stefano, Zampella, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324103/
https://ncbi.nlm.nih.gov/pubmed/28233865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43290
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