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Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
Bile acids are extensively investigated for their potential in the treatment of human disorders. The liver X receptors (LXRs), activated by oxysterols and by a secondary bile acid named hyodeoxycholic acid (HDCA), have been found essential in the regulation of lipid homeostasis in mammals. Unfortuna...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324103/ https://ncbi.nlm.nih.gov/pubmed/28233865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43290 |
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