Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

Benzer Materyaller

• Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties
  Yazar:: Finamore, Claudia, ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1
  Yazar:: Di Leva, Francesco Saverio, ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
  Yazar:: De Marino, Simona, ve diğerleri
  Baskı/Yayın Bilgisi: (2017)
• Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
  Yazar:: Festa, Carmen, ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism
  Yazar:: Di Leva, Francesco Saverio, ve diğerleri
  Baskı/Yayın Bilgisi: (2015)