Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Exposure of breast cancer cells to hypoxia increases the percentage of breast cancer stem cells (BCSCs), which are required for tumor initiation and metastasis, and this response is dependent on the activity of hypoxia-inducible factors (HIFs). We previously reported that exposure of breast cancer c...

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Publicat a:Oncotarget
Autors principals: Zhang, Chuanzhao, Zhi, Wanqing Iris, Lu, Haiquan, Samanta, Debangshu, Chen, Ivan, Gabrielson, Edward, Semenza, Gregg L.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323097/
https://ncbi.nlm.nih.gov/pubmed/27590511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11743
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