Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Exposure of breast cancer cells to hypoxia increases the percentage of breast cancer stem cells (BCSCs), which are required for tumor initiation and metastasis, and this response is dependent on the activity of hypoxia-inducible factors (HIFs). We previously reported that exposure of breast cancer c...

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Pubblicato in:Oncotarget
Autori principali: Zhang, Chuanzhao, Zhi, Wanqing Iris, Lu, Haiquan, Samanta, Debangshu, Chen, Ivan, Gabrielson, Edward, Semenza, Gregg L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Priority Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323097/
https://ncbi.nlm.nih.gov/pubmed/27590511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11743
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