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Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment

Breast cancer stem cells (BCSCs), which are characterized by a capacity for unlimited self-renewal and for generation of the bulk cancer cell population, play a critical role in cancer relapse and metastasis. Hypoxia is a common feature of the cancer microenvironment that stimulates the specificatio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lan, Jie, Lu, Haiquan, Samanta, Debangshu, Salman, Shaima, Lu, You, Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187157/
https://ncbi.nlm.nih.gov/pubmed/30242135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809695115
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