Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

Intratumoral hypoxia, which is associated with breast cancer metastasis and patient mortality, increases the percentage of breast cancer stem cells (BCSCs) but the underlying molecular mechanisms have not been delineated. Here we report that hypoxia-inducible factor 1 (HIF-1) triggers the expression...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Xiang, Lisha, Gilkes, Daniele M., Hu, Hongxia, Takano, Naoharu, Luo, Weibo, Lu, Haiquan, Bullen, John W., Samanta, Debangshu, Liang, Houjie, Semenza, Gregg L.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
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Priority Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350363/
https://ncbi.nlm.nih.gov/pubmed/25587023
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