Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

Intratumoral hypoxia, which is associated with breast cancer metastasis and patient mortality, increases the percentage of breast cancer stem cells (BCSCs) but the underlying molecular mechanisms have not been delineated. Here we report that hypoxia-inducible factor 1 (HIF-1) triggers the expression...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Xiang, Lisha, Gilkes, Daniele M., Hu, Hongxia, Takano, Naoharu, Luo, Weibo, Lu, Haiquan, Bullen, John W., Samanta, Debangshu, Liang, Houjie, Semenza, Gregg L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2014
Aiheet:
Priority Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350363/
https://ncbi.nlm.nih.gov/pubmed/25587023
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