Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

Intratumoral hypoxia, which is associated with breast cancer metastasis and patient mortality, increases the percentage of breast cancer stem cells (BCSCs) but the underlying molecular mechanisms have not been delineated. Here we report that hypoxia-inducible factor 1 (HIF-1) triggers the expression...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Xiang, Lisha, Gilkes, Daniele M., Hu, Hongxia, Takano, Naoharu, Luo, Weibo, Lu, Haiquan, Bullen, John W., Samanta, Debangshu, Liang, Houjie, Semenza, Gregg L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2014
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350363/
https://ncbi.nlm.nih.gov/pubmed/25587023
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