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Plk1 Regulates Activation of the Anaphase Promoting Complex by Phosphorylating and Triggering SCF(βTrCP)-dependent Destruction of the APC Inhibitor Emi1
Progression through mitosis requires activation of cyclin B/Cdk1 and its downstream targets, including Polo-like kinase and the anaphase-promoting complex (APC), the ubiquitin ligase directing degradation of cyclins A and B. Recent evidence shows that APC activation requires destruction of the APC i...
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| Gepubliceerd in: | Mol Biol Cell |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Cell Biology
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC532041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15469984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-07-0598 |
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