Загрузка...
Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels
Cardiac long QT syndrome type 2 is caused by mutations in the human ether a go-go-related gene (hERG) potassium channel, many of which cause misfolding and degradation at the endoplasmic reticulum instead of normal trafficking to the cell surface. The Hsc70/Hsp70 chaperones assist the folding of the...
Сохранить в:
| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313101/ https://ncbi.nlm.nih.gov/pubmed/27998983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752618 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|