Nalaganje...
PINK1 primes parkin-mediated ubiquitination of PARIS in dopaminergic neuronal survival
Mutations in PTEN-induced putative kinase 1 (PINK1) and parkin cause autosomal-recessive Parkinson’s disease through a common pathway involving mitochondrial quality control. Parkin inactivation leads to accumulation of the parkin interacting substrate (PARIS, ZNF746) that plays an important role in...
Shranjeno v:
| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312976/ https://ncbi.nlm.nih.gov/pubmed/28122242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.090 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|