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The transcriptional regulator Aire binds to and activates super-enhancers

Aire is a transcription factor that controls T cell tolerance by inducing the expression of a large repertoire of genes specifically in thymic stromal cells. It interacts with scores of protein partners of diverse functional classes. Here we showed that Aire and some of its partners, notably those i...

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Bibliografische gegevens
Gepubliceerd in:Nat Immunol
Hoofdauteurs: Bansal, Kushagra, Yoshida, Hideyuki, Benoist, Christophe, Mathis, Diane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310976/
https://ncbi.nlm.nih.gov/pubmed/28135252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3675
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