Loading...
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1
BACKGROUND: Leflunomide is a low-molecular-weight compound that is widely used in the treatment of rheumatoid arthritis. Although leflunomide is thought to act through the inhibition of the de novo pyrimidine synthesis, the molecular mechanism of the drug remains largely unknown. We investigated the...
Na minha lista:
| Udgivet i: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5304395/ https://ncbi.nlm.nih.gov/pubmed/28193225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1131-x |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|