Suppressive effect of leflunomide metabolite (A77 1726) on metalloproteinase production in IL-1β stimulated rheumatoid synovial fibroblasts

Leflunomide, an isoxazol derivative structurally unrelated to other immunomodulatory drugs, has proven to be efficacious in the treatment of rheumatoid arthritis (RA). This study was conducted to elucidate the mechanism by which leflunomide mediated antirheumatic effects. We investigated the effects...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: MIGITA, K, MIYASHITA, T, ISHIBASHI, H, MAEDA, Y, NAKAMURA, M, YATSUHASHI, H, IDA, H, KAWAKAMI, A, AOYAGI, T, KAWABE, Y, EGUCHI, K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2004
Gaiak:
Clinical Studies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809130/
https://ncbi.nlm.nih.gov/pubmed/15320915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02555.x
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