TNF-alpha-mediated expression of membrane-type matrix metalloproteinase in rheumatoid synovial fibroblasts.

Degradation of the extracellular matrix plays an important role in rheumatoid articular destruction. Rheumatoid synovial fibroblasts secrete a large amount of matrix-degrading metalloproteinases (MMPs), which initiate tissue damage by proteolytic degradation of collagens and proteoglycans. Cytokines...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Migita, K, Eguchi, K, Kawabe, Y, Ichinose, Y, Tsukada, T, Aoyagi, T, Nakamura, H, Nagataki, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456590/
https://ncbi.nlm.nih.gov/pubmed/9014820
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi