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The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function
Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis (RA), exhibits anti-inflammatory, antiproliferative and immunosuppressive effects. Although most of the beneficial effects of leflunomide have been attributed to its antimetabolite activity, main...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174963/ https://ncbi.nlm.nih.gov/pubmed/15899055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1727 |
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