The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes

Leflunomide is an immunomodulatory agent used for the treatment of rheumatoid arthritis. In this study, we investigated the effect of A77 1726 – the active metabolite of leflunomide – on the production of IL-1 receptor antagonist (IL-1Ra) by human synovial fibroblasts and articular chondrocytes. Cel...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Palmer, Gaby, Burger, Danielle, Mezin, Françoise, Magne, David, Gabay, Cem, Dayer, Jean-Michel, Guerne, Pierre-André
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15142263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar1157
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