The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes

Leflunomide is an immunomodulatory agent used for the treatment of rheumatoid arthritis. In this study, we investigated the effect of A77 1726 – the active metabolite of leflunomide – on the production of IL-1 receptor antagonist (IL-1Ra) by human synovial fibroblasts and articular chondrocytes. Cel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arthritis Res Ther
Päätekijät: Palmer, Gaby, Burger, Danielle, Mezin, Françoise, Magne, David, Gabay, Cem, Dayer, Jean-Michel, Guerne, Pierre-André
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2004
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15142263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar1157
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