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Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) affects 1 in 500 individuals and is an important cause of arrhythmias and heart failure. Clinically, HCM is characterized as causing hypercontractility, and therapies are aimed toward controlling the hyperactive physiology. Mutations in the β-cardiac myosin comprise...
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| Gepubliceerd in: | Sci Adv |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Association for the Advancement of Science
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5302870/ https://ncbi.nlm.nih.gov/pubmed/28246639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601959 |
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