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The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations
Hypertrophic cardiomyopathy (HCM) is primarily caused by mutations in β-cardiac myosin and myosin-binding protein-C (MyBP-C). Changes in the contractile parameters of myosin measured so far do not explain the clinical hypercontractility caused by such mutations. We propose that hypercontractility is...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737966/ https://ncbi.nlm.nih.gov/pubmed/28481356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3408 |
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