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Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization

Recently, the use of mammalian target of rapamycin (mTOR) inhibitors, in particular rapamycin (Rp), has been suggested to improve the treatment of neurodegenerative diseases. However, as Rp is a strong immunosuppressant, specific delivery to the brain has been postulated to avoid systemic exposure....

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Vydáno v:Nanomaterials (Basel)
Hlavní autoři: Polchi, Alice, Magini, Alessandro, Mazuryk, Jarosław, Tancini, Brunella, Gapiński, Jacek, Patkowski, Adam, Giovagnoli, Stefano, Emiliani, Carla
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302501/
https://ncbi.nlm.nih.gov/pubmed/28335215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano6050087
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