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Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization

Recently, the use of mammalian target of rapamycin (mTOR) inhibitors, in particular rapamycin (Rp), has been suggested to improve the treatment of neurodegenerative diseases. However, as Rp is a strong immunosuppressant, specific delivery to the brain has been postulated to avoid systemic exposure....

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Polchi, Alice, Magini, Alessandro, Mazuryk, Jarosław, Tancini, Brunella, Gapiński, Jacek, Patkowski, Adam, Giovagnoli, Stefano, Emiliani, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302501/
https://ncbi.nlm.nih.gov/pubmed/28335215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano6050087
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